Advanced Biological Laboratories (ABL) / TherapyEdge INC

Core business

Advanced Biological Laboratories (ABL) S.A., is a medical data technology company founded in 2000 as a spin-off from CRP-Santé (now the Luxembourg Institute of Health (LIH)). ABL took control of TherapyEdge, Inc. in 2004 and in 2013 acquired the rights to all viral hepatitis B & C related assets from EVIVAR MEDICAL. ABL has a comprehensive suite of healthcare management tools, including TherapyEdge®, ViroScore®, SeqHepB, DeepChek®, VisibleChek®, HepatiC™ and OncoChek™, which are used for data and patient management, monitoring and personalised reporting applications. In 2012, some of ABL’s products received CE-marking for IVD use. ABL’s products offer infectious disease clinicians and virology laboratories optimal and efficient IT solutions, for sequencing, clinical genotyping and drug resistance analysis, including powerful fully integrated databases and analysis systems combining standard and high-throughput next generation sequencing data.

Products & services

ABL develops and implements several products and services around its web-based and local TherapyEdge® Box System to deliver the best therapies for people living with complex, chronic diseases.

Major HealthTech projects

Since 2000, ABL has leveraged a large experience in virology (HIV and viral hepatitis) for patient management either from clinical, virological and molecular sides. ABL has acquired the assets of TherapyEdge® Inc. for HIV and Evivar Medical Pty for HBV. These assets are patents, software and knowledge databases. ABL continue investing resources in infectious diseases to support its product portfolio.

ABL recently inked an agreement with LIH for getting the exclusive commercial rights on COMET technology.

ABL is also engaging strong collaborations in the fields of microbiology and human genetics for developing new applications in tuberculosis and oncology.

ABL continues its efforts to bring the latest technologies for server virtualisation, web development with strong capacities of data security and data encryption, bioinformatics scripts and methods for fast and reliable data management and analysis of next generation sequencing information.

Technical / technological capabilities

ABL is able to develop secure network (intranet, internet, VPN) platforms for the electronic management of clinical information between distributed units. ABL’s technology is a ready-to-run solution for all the technical problems that users face. The developed platforms are based on state-of-the-art technologies. ABL offers a service adapted to each clinical setting and can implement electronic case report forms.

ABL is also able to develop specifically:

• algorithm-based genotype interpretation systems;
• tools for the management of sequences; and
• advanced genetic analysis tools to integrate complex clinical and virological information.

ABL products lie on a proprietary platform server (hardware, virtual or internet-based). End-users access the various pieces of software using web-browser. It could be used by clinicians, pathology laboratories, private insurance companies, diagnostics and pharmaceutical companies.

Main customers / collaborations

• Luxembourg Institute of Health (LIH);
• Latin American Liver Research Awareness and Educational Network (LALREAN) for HCV;
• AEEH, Spanish Association of Hepatologists for HCV;
• Spanish HIV Foundation (Badalona, Barcelona) for HIV & NGS;
• South Africa National Health Laboratory Service (NHLS);
• European Society for Antiviral Resistance;
• TINN2 (FP7 EU Project);
• Roche Diagnostics International and other major Pharma and Dx companies;
• Tute Genomics (Oncology, human genetics).